Safety and research
Definition
A contraindication is a situation in which a device or intervention should not be used because the known risk clearly outweighs any possible benefit.
Aliases and abbreviations
contraindicated use
Editorial record
Published: August 25, 2026 · Reviewed: August 25, 2026
Expanded definition
Contraindications are product- and use-specific. They should describe known situations where use creates an unacceptable risk, rather than theoretical possibilities copied from unrelated devices.
A contraindication is stronger than a precaution. A precaution calls for additional care, information, or professional assessment, while a contraindication states that use should be avoided.
For any specific product, the final instructions for use, labeling, and current safety information take priority over a general educational definition.
What the term does not establish
Why the distinction matters
Precise labeling prevents research exclusions, uncertainty, and known unacceptable risks from being collapsed into one list.
Related terms
Safety and research
Safety and research
Safety and research
Safety and research
Stimulation methods
Stimulation methods
Editorial scope
This glossary entry supports general education. It does not diagnose, recommend treatment, or transfer findings from one VNS method, protocol, or device to another.